In this comedy directed by Ben Falcone, McCarthy plays Tammy, who after losing her job and learning that her husband has been unfaithful, hits the road with her hard-drinking grandmother.Co-starring Ben Falcone, Susan Sarandon, Kathy Bates and Allison Janney. Asked if she has had a memorable trip that inspired her film:
One time, I did have to pull over. I was like, ‘I’m driving this time. That will keep me awake.’ If I’m caged, I immediately go out. It was before the 405. I just remember Ben going, ‘Oh, my god, you’re swerving!’ We did not make it 15 minutes from the house, and I had to pull over so that we could switch. I’m good for the first 10 minutes, and then I’m out, so I’m super helpful. After we shot this, we drove all the way back to Los Angeles from Niagara Falls, with our kids. That was a doozy.