Gordon-Levitt portrays a cancer-stricken radio writer named Adam Lerner in this comedy-drama film directed by Jonathan Levine. Based on a true story, the film revolves around his character’s discovery of his illness and how it changes his life and that of his friends and family. He is joined by actor Seth Rogen who plays his best friend Kyle, Anjelica Huston who plays his overbearing mother Diane Lerner, and Anna Kendrick who plays his therapist Katherine McKay. On accepting the role of Adam:
First of all it’s just a good script, which is just rare to come by. You know I read a lot of scripts and most of them are just sort of not so good. You know, the characters don’t feel like human beings. They feel like plot devices, stereotypes. Especially scripts that make me laugh. It’s very, very rare to come by a well-written funny script. And so when I read “50/50,” I was really taken with it off the bat.